Gene

bin1b

ID
ZDB-GENE-030425-1
Name
bridging integrator 1b
Symbol
bin1b Nomenclature History
Previous Names
  • bin1
  • cb57 (1)
  • zgc:86701
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have phospholipid binding activity and tau protein binding activity. Involved in cardiac muscle contraction. Predicted to localize to plasma membrane and synaptic vesicle. Human ortholog(s) of this gene implicated in breast carcinoma; centronuclear myopathy 2; and prostate adenocarcinoma. Is expressed in adaxial cell; cardiovascular system; musculature system; and somite. Orthologous to human BIN1 (bridging integrator 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Hong et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bin1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
centronuclear myopathy 2 Alliance Centronuclear myopathy 2 255200
Associated With bin1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR004148 BAR domain
Domain IPR035471 Amphiphysin 2, SH3 domain
Family IPR003005 Amphiphysin
Homologous_superfamily IPR027267 AH/BAR domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length AH/BAR domain superfamily Amphiphysin Amphiphysin 2, SH3 domain BAR domain SH3 domain SH3-like domain superfamily
UniProtKB:F8W278 253
UniProtKB:F8W5X7 204
UniProtKB:A0A2R8QMI5 576
UniProtKB:F1QRX4 364
UniProtKB:F8W5F8 212
UniProtKB:Q66I38 364
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations