Gene

krt8

ID
ZDB-GENE-030411-5
Name
keratin 8
Symbol
krt8 Nomenclature History
Previous Names
  • krt2-8 (1)
  • cb186 (1)
  • DreK8 (1)
  • etID33550.23 (1)
  • etID43142.23 (1)
  • etID43142.8 (1)
  • sb:cb186 (1)
  • wu:fa20h05 (1)
  • wu:fa95h10 (1)
  • wu:fb96c06 (1)
  • zf-K8 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in liver cirrhosis. Is expressed in several structures, including EVL; cardiovascular system; integument; pectoral fin; and sensory system. Orthologous to several human genes including KRT8 (keratin 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With krt8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cirrhosis, cryptogenic 215600
{Cirrhosis, noncryptogenic, susceptibility to} 215600
Associated With krt8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR032444 Keratin type II head
Domain IPR039008 Intermediate filament, rod domain
Family IPR003054 Keratin, type II
Homologous_superfamily IPR042180 Intermediate filament, rod domain, coil 1B
Domain Details Per Protein
Protein Length Intermediate filament protein, conserved site Intermediate filament, rod domain Intermediate filament, rod domain, coil 1B Keratin, type II Keratin type II head
UniProtKB:A0A2R8Q6V3 516
UniProtKB:Q6NWF6 520
UniProtKB:A8WGN0 520
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations