ZFIN ID: ZDB-GENE-030411-5
Gene Name: keratin 8
Gene Symbol: krt8
Sequence Ontology ID : SO:0000704

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Previous Names: krt2-8 (1), cb186 (1), DreK8 (1), etID33550.23 (1), etID43142.23 (1), etID43142.8 (1), sb:cb186 (1), wu:fa20h05 (1), wu:fa95h10 (1), wu:fb96c06 (1), zf-K8 (1)

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 22 figures from 10 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2001 [cb186]
  6 figures (14 images) from Thisse et al., 2004 [MGC:85764]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
  artery, breeding tubercle, cardiovascular system, epidermis (all 22) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1629 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31084 Point Mutation Unknown Splice Site ENU
    sa37629 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43921 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-krt8 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH krt8 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cirrhosis, cryptogenic 215600
    {Cirrhosis, noncryptogenic, susceptibility to} 215600
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cytoplasm (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001664 (1)
  • InterPro:IPR003054 (1)
  • InterPro:IPR018039 (1)
  • InterPro:IPR032444 (1)
  • PROSITE:PS00226 (1)
  • PROSITE:PS51842 (1)
  • Pfam:PF00038 (1)
  • Pfam:PF16208 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA krt8-001 (1) 2214
    ncRNA krt8-002 (1) 784
    krt8-003 (1) 793
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM krt8
    Tg(-0.6opn1lw1-krt8:GFP), Tg(-1.9mylpfa:fsta,krt8:EGFP), Tg(krt8:LEXPR,LEXOP:EGFP), Tg(krt8:LEXPR,LEXOP:EGFP-kras_G12V)
    MARKER RELATIONSHIPS
    krt8Contained in: [BAC] CH211-133J6 (1) (order this)
    krt8Encodes: [EST] cb186 (2) (order this), fa20h05 (1), fa95h10 (1), fb96c06 (1)
    [cDNA] MGC:85764 (1) (order this), MGC:174782 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200080 (1) 2220bp
    Genomic GenBank:CR450756 (1) 131145bp
    Select Tool
    Polypeptide UniProtKB:A8WGN0 (1) 520aa
    Sequence Clusters UniGene:75900 (1)
    Sequence Information (all 30)
    OTHER krt8 GENE PAGES
  • Alliance (1)
  • Gene:797433 (1)
  • VEGA:OTTDARG00000021241 (1)
  • Ensembl(GRCz10):ENSDARG00000058358 (1)
  • ORTHOLOGY for krt8 (Chr: 23)
    CITATIONS (56)