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General Information
ZIRC
ZFIN ID: ZDB-GENE-030327-4
Gene Name: iodothyronine deiodinase 2
Gene Symbol: dio2
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: D2 (1), Deio2 (1), cb684 (1)

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits thyroxine 5'-deiodinase activity. Involved in several processes, including chordate embryonic development; developmental pigmentation; and regulation of neural retina development. Predicted  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
lv1 Small Deletion Unknown Unknown ZINC_FINGER_NUCLEASE
lv2 Insertion Unknown Frameshift, Premature Stop ZINC_FINGER_NUCLEASE
Targeting reagents:
DISEASE ASSOCIATED WITH dio2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH dio2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to hormone (more)
Cellular Component integral component of membrane (more)
Molecular Function thyroxine 5'-deiodinase activity (more)
GO Terms (all 14)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA dio2-201 (1) 2166
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDS
Addgene
CONSTRUCTS WITH SEQUENCES FROM dio2 No data available
MARKER RELATIONSHIPS
dio2Contained in: [BAC] DKEY-245F17 (1) (order this)
dio2Contains: [STS] chunp30595
dio2Encodes: [EST] cb684 (1) (order this)
[cDNA] MGC:73279 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_212789 (1) 2212bp
Genomic GenBank:CR381576 (1) 185749bp
Select Tool
Polypeptide UniProtKB:E9QGM3 (1) 258aa
Sequence Clusters UniGene:12949 (1)
Sequence Information (all 23)
ORTHOLOGY for dio2 (Chr: 17)
CITATIONS (127)