ZFIN ID: ZDB-GENE-030131-688
Gene Name: glutamate-ammonia ligase (glutamine synthase) a
Gene Symbol: glula    Nomenclature History

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Previous Names: cb195 (1), cb757 (1), etID49849.2 (1), fb39g09, fd19d09, gs (1), gso1 (1), sb:cb195 (1), wu:fb39g09, wu:fd19d09 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have glutamate-ammonia ligase activity. Predicted to be involved in glutamine biosynthetic process. Predicted to localize to cytoplasm. Is expressed in several structures, including cardiovascular system; digestive system; hematopoietic system; musculature system; and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; and temporal lobe epilepsy. Orthologous to human GLUL (glutamate-ammonia ligase).
Genome Resources: Alliance (1),  Gene:100000775 (1),  Ensembl(GRCz11):ENSDARG00000099776 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1387 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-glula N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH glula HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Glutamine deficiency, congenital 610015
DISEASE ASSOCIATED WITH glula VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process glutamine biosynthetic process (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA glula-202 (1)    Ensembl 1974
ncRNA glula-002 (1)    Ensembl 780
glula-003 (1)    Ensembl 435
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM glula No data available
MARKER RELATIONSHIPS
glula Contained in: [BAC] CH211-218C8 (1)
glula Encodes: [EST] cb195 (2) (order this), cb757 (1) (order this), fb39g09 (order this), fb44b10 (1) (order this), fd19d09 (1)
[cDNA] MGC:63917 (1), MGC:198092 (1), MGC:198096 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_181559 (1) 1968 nt
Genomic GenBank:CT027770 (1) 196559 nt
Select Tool
Polypeptide UniProtKB:Q7M569 (1) 371 aa
Sequence Information (all 31)
ORTHOLOGY for glula ( Chr: 2 )
CITATIONS (43)