ZFIN ID: ZDB-GENE-030131-6048
Gene Name: enolase 1a, (alpha)
Gene Symbol: eno1a    Nomenclature History

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Previous Names: eno1, wu:fi32b03, wu:fk58e02, zgc:73152

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have magnesium ion binding activity and phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process. Predicted to localize to phosphopyruvate hydratase complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including axis; margin; nervous system; neural tube; and trigeminal placode. Orthologous to human ENO1 (enolase 1).
Genome Resources: Alliance (1),  Gene:334116 (1),  Ensembl(GRCz11):ENSDARG00000022456 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24319 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eno1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Enolase deficiency
    DISEASE ASSOCIATED WITH eno1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glycolytic process (more)
    Cellular Component phosphopyruvate hydratase complex (more)
    Molecular Function magnesium ion binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA eno1a-201 (1)    Ensembl 1996
    eno1a-202 (1)    Ensembl 986
    ncRNA eno1a-003 (1)    Ensembl 738
    eno1a-004 (1)    Ensembl 848
    eno1a-005 (1)    Ensembl 738
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM eno1a No data available
    MARKER RELATIONSHIPS
    eno1a Contained in: [BAC] CH211-28E16 (1)
    eno1a Encodes: [EST] fi32b03, fk58e02 (1)
    [cDNA] MGC:73152 (1), MGC:86675 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212722 (1) 1797 nt
    Genomic GenBank:CR388207 (1) 191838 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q1X2 (1) 432 aa
    Sequence Information (all 19)
    ORTHOLOGY for eno1a ( Chr: 23 )
    CITATIONS (42)