ZFIN ID: ZDB-GENE-030131-5045
Gene Name: CCHC-type zinc finger, nucleic acid binding protein a
Gene Symbol: cnbpa    Nomenclature History

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Previous Names: CNBP (1), zCNBP (1), cellular nucleic acid binding protein (1), fe36b09, wu:fe36b09, zff9 (1), zgc:63625 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Exhibits chromatin binding activity and nucleic acid binding activity. Involved in several processes, including neural crest cell fate specification; regulation of transcription, DNA-templated; and skeletal system development. Predicted to localize to cytoplasm. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; nervous system; and pectoral fin. Human ortholog(s) of this gene implicated in myotonic dystrophy type 2. Orthologous to several human genes including CNBP (CCHC-type zinc finger nucleic acid binding protein).
Genome Resources: Alliance (1),  Gene:326846 (1),  Ensembl(GRCz11):ENSDARG00000045776 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37604 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cnbpa N/A 4
    MO2-cnbpa N/A 6
    MO3-cnbpa N/A 1
    DISEASE ASSOCIATED WITH cnbpa HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    myotonic dystrophy type 2 Alliance Myotonic dystrophy 2 602668
    DISEASE ASSOCIATED WITH cnbpa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription by RNA polymerase II (more)
    Cellular Component cytoplasm (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cnbpa-201 (1)    Ensembl 1573
    cnbpa-202 (1)    Ensembl 1060
    cnbpa-203 (1)    Ensembl 928
    cnbpa-204 (1)    Ensembl 765
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cnbpa Rabbit WB 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cnbpa
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(cnbpa:EGFP) cnbpa EGFP Danio rerio 1 3
    Tg(Xla.Eef1a1:cnbpa-EGFP) cnbpaEGFP Danio rerioXenopus laevis 1 3
    Tg(Xla.Eef1a1:cnbpa_M1-G35del-EGFP) cnbpaEGFP Danio rerioXenopus laevis 1 2
    MARKER RELATIONSHIPS
    cnbpa Contained in: [Fosmid] CH1073-66C17 (1)
    cnbpa Encodes: [EST] fe36b09
    [cDNA] MGC:63625 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199749 (1) 1614 nt
    Genomic GenBank:CU571070 (1) 40511 nt
    Select Tool
    Polypeptide UniProtKB:F1Q6Z5 (1) 163 aa
    Sequence Information (all 22)
    ORTHOLOGY for cnbpa ( Chr: 23 )
    CITATIONS (36)