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ZIRC
ZFIN ID: ZDB-GENE-030131-2905
Gene Name: FA complementation group I
Gene Symbol: fanci    Nomenclature History

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Previous Names: fc21c10, wu:fc21c10, zgc:152941

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have DNA polymerase binding activity. Predicted to be involved in DNA repair. Human ortholog(s) of this gene implicated in Fanconi anemia and Fanconi anemia complementation group I. Is expressed in central nervous system; head; heart; pectoral fin; and rostral blood island. Orthologous to human FANCI (FA complementation group I).
Genome Resources: Alliance (1),  Gene:324185 (1),  Ensembl(GRCz11):ENSDARG00000026224 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hg54 Small Deletion Exon 13 Unknown CRISPR
hg55 Indel Unknown Unknown CRISPR
sa8892 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9207 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38013 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38014 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39472 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fanci 1
    DISEASE ASSOCIATED WITH fanci HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Fanconi anemia complementation group I Alliance Fanconi anemia, complementation group I 609053
    DISEASE ASSOCIATED WITH fanci VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process DNA repair (more)
    Cellular Component cellular_component (more)
    Molecular Function DNA polymerase binding (more)
    GO Terms (all 3)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fanci-202 (1)    Ensembl 4488
    ncRNA fanci-002 (1) 3400
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fanci No data available
    MARKER RELATIONSHIPS
    fanci Contained in: [BAC] CH211-198O8 (1) (order this)
    fanci Encodes: [EST] fc21c10, fw80g08
    [cDNA] MGC:152941 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077312 (1) 4488 bp
    Genomic GenBank:CR854881 (1) 193195 bp
    Select Tool
    Polypeptide UniProtKB:F1R3B9 (1) 1327 aa
    Sequence Clusters UniGene:77582 (1)
    Sequence Information (all 18)
    ORTHOLOGY for fanci ( Chr: 25 )
    CITATIONS (22)