ZFIN ID: ZDB-FIG-190904-2
Ramanagoudr-Bhojappa et al., 2018 - Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility. PLoS Genetics   14:e1007821 Full text @ PLoS Genet.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Adult

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
brca2hg45/hg45 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
brip1hg56/hg56 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
brip1hg57/hg57 standard conditions Adult female organism decreased amount, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
ercc4hg68/hg68 standard conditions Adult female organism decreased amount, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancahg41/hg41 standard conditions Adult female organism decreased amount, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancbhg42/hg42 standard conditions Adult female organism decreased amount, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancchg43/hg43 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancd2hg47/hg47 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancehg48/hg48 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancfhg50/hg50 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancghg53/hg53 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancihg54/hg54 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fanclhg59/hg59 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
fancmhg60/hg60 standard conditions Adult female organism decreased amount, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
palb2hg62/hg62 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
rad51chg65/hg65 standard conditions Adult female organism decreased amount, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
slx4hg66/hg66 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
slx4hg67/hg67 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
ube2thg70/hg70 standard conditions Adult female organism absent, abnormal
Adult female sex determination decreased occurrence, abnormal
Adult male organism increased amount, abnormal
Adult male sex determination increased occurrence, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.