Gene
npm1a
- ID
- ZDB-GENE-021028-1
- Name
- nucleophosmin 1a
- Symbol
- npm1a Nomenclature History
- Previous Names
-
- npm1
- sb:cb487
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity; chromatin binding activity; and histone binding activity. Involved in hemopoiesis and regulation of apoptotic process. Localizes to nucleolus. Is expressed in several structures, including digestive system; fin bud; hematopoietic cell; nervous system; and neural tube. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NPM1 (nucleophosmin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb487 (32 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Bolli et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Leukemia, acute myeloid, somatic | 601626 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Nucleophosmin, C-terminal | Nucleoplasmin core domain | Nucleoplasmin core domain superfamily | Nucleoplasmin family |
---|---|---|---|---|---|
UniProtKB:E7FCU0
|
279 |
Interactions and Pathways
No data available
Plasmids
No data available