ZFIN ID: ZDB-GENE-020802-3
Gene Name: histocompatibility (minor) 13
Gene Symbol: hm13    Nomenclature History

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Previous Names: cb228 (1), spp (1), wu:fc11a06, zgc:86862

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have aspartic endopeptidase activity, intramembrane cleaving. Involved in regulation of neuron apoptotic process. Predicted to localize to integral component of cytoplasmic side of endoplasmic reticulum membrane and integral component of lumenal side of endoplasmic reticulum membrane. Is expressed in several structures, including alar plate midbrain region; axial mesoderm; digestive system; immature eye; and nervous system. Orthologous to human HM13 (histocompatibility minor 13).
Genome Resources: Alliance (1),  Gene:259190 (1),  Ensembl(GRCz11):ENSDARG00000037846 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022786Tg Transgenic Insertion Unknown Unknown DNA
sa24231 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hm13 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hm13 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of neuron apoptotic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function aspartic-type endopeptidase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hm13-201 (1)    Ensembl 1953
    ncRNA hm13-002 (1)    Ensembl 749
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hm13 No data available
    MARKER RELATIONSHIPS
    hm13 Contained in: [BAC] DKEYP-44B8 (1)
    hm13 Encodes: [EST] cb228 (1) (order this), fc11a06 (1), IMAGE:6903340 (1)
    [cDNA] MGC:56660 (1), MGC:86862 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212572 (1) 1985 nt
    Genomic GenBank:BX323461 (1) 169310 nt
    Select Tool
    Polypeptide UniProtKB:Q6IQA7 (1) 366 aa
    Sequence Information (all 21)
    ORTHOLOGY for hm13 ( Chr: 23 )
    CITATIONS (25)