Gene

mcm7

ID
ZDB-GENE-020419-27
Name
minichromosome maintenance complex component 7
Symbol
mcm7 Nomenclature History
Previous Names
  • chunp6911
  • MCM7 minichromosome maintenance deficient 7
  • nyz175 (1)
  • sr:nyz175 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to contribute to single-stranded 3'-5' DNA helicase activity. Involved in regulation of cilium assembly. Predicted to localize to MCM complex and nucleus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MCM7 (minichromosome maintenance complex component 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mcm7 Human Ortholog
No data available
Associated With mcm7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018525 Mini-chromosome maintenance, conserved site
Domain IPR001208 MCM domain
Domain IPR003593 AAA+ ATPase domain
Domain IPR027925 MCM N-terminal domain
Domain IPR033762 MCM OB domain
Domain IPR041562 MCM, AAA-lid domain
Family IPR008050 DNA replication licensing factor Mcm7
Family IPR031327 Mini-chromosome maintenance protein
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain DNA replication licensing factor Mcm7 MCM, AAA-lid domain MCM domain MCM N-terminal domain MCM OB domain Mini-chromosome maintenance, conserved site Mini-chromosome maintenance protein Nucleic acid-binding, OB-fold P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A0E3D6N5 104
UniProtKB:Q7ZVL6 721
UniProtKB:A0A0R4IM40 130
UniProtKB:A0A0J9YJK4 397
UniProtKB:A0A0R4IRW9 75
UniProtKB:Q8JGR9 194
UniProtKB:A0A0R4IF39 608
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations