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General Information
ZIRC
ZFIN ID: ZDB-GENE-020220-1
Gene Name: amyloid beta (A4) precursor protein b
Gene Symbol: appb
Sequence Ontology ID : SO:0001217

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Attributions

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Previous Names: wu:fc43a03 (1), zgc:92771

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have heparin binding activity; serine-type endopeptidase inhibitor activity; and transition metal ion binding activity. Involved in several processes, including convergent extension;  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016566Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la029590Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa327 Point Mutation Unknown Premature Stop ENU
    sa34693 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41475 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH appb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Alzheimer's disease 1 Alzheimer disease 1, familial 104300
    APP-related cerebral amyloid angiopathy Cerebral amyloid angiopathy, Dutch, Italian, Iowa, Flemish, Arctic variants 605714
    DISEASE ASSOCIATED WITH appb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA appb-203 (1) 2256
    appb-205 (1) 4099
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDS No data available
    MARKER RELATIONSHIPS
    appb Contained in: [BAC] DKEY-192G7 (1) (order this)
    appb Encodes: [EST] fc43a03 (1)
    [cDNA] MGC:92771 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_152886 (1) 4066 bp
    Genomic GenBank:CR759841 (1) 94752 bp
    Select Tool
    Polypeptide UniProtKB:B0V0E5 (1) 751 aa
    Sequence Clusters UniGene:2615 (1)
    Sequence Information (all 34)
    ORTHOLOGY for appb ( Chr: 9 )
    CITATIONS (51)