Gene

gbx1

ID
ZDB-GENE-020117-2
Name
gastrulation brain homeobox 1
Symbol
gbx1 Nomenclature History
Previous Names
  • cb619 (1)
  • fj77a06
  • wu:fj77a06 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in cerebellum development; midbrain-hindbrain boundary morphogenesis; and regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation. Predicted to localize to nucleus. Is expressed in several structures, including nervous system; neural keel; neural plate; presumptive neural plate; and ventral mesoderm. Orthologous to human GBX1 (gastrulation brain homeobox 1).
Genome Resources
Note
None
Expression
All Expression Data
37 figures from 18 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Rhinn et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gbx1 Human Ortholog
No data available
Associated With gbx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Family IPR031251 Homeobox protein GBX-1
Family IPR042982 Homeobox protein GBX-1/2
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily Homeobox protein GBX-1 Homeobox protein GBX-1/2
UniProtKB:Q90ZB2 316
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations