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General Information
ZIRC
ZFIN ID: ZDB-GENE-020102-1
Gene Name: chemokine (C-X-C motif) receptor 4a
Gene Symbol: cxcr4a
Sequence Ontology ID : SO:0000704

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Previous Name: cb824 (1)

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes, including ameboidal-type cell migration; cell morphogenesis; and vasculature  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a169 Small Deletion Unknown Frameshift CRISPR
s421 Unknown Unknown Unknown
sa1098 Point Mutation Unknown Premature Stop ENU
um20 Small Deletion Unknown Unknown ZINC_FINGER_NUCLEASE
um21 Indel Unknown Frameshift, Premature Stop
Targeting reagents:
DISEASE ASSOCIATED WITH cxcr4a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
WHIM syndrome WHIM syndrome 193670
Myelokathexis, isolated
DISEASE ASSOCIATED WITH cxcr4a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell migration involved in sprouting angiogenesis (more)
Cellular Component integral component of membrane (more)
Molecular Function chemokine receptor activity (more)
GO Terms (all 27)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA cxcr4a-201 (1) 1636
cxcr4a-202 (1) 1227
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM cxcr4a
MARKER RELATIONSHIPS
cxcr4aContained in: [BAC] CH73-268G8 (1) (order this)
cxcr4aEncodes: [EST] cb824 (1)
[cDNA] MGC:56609 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131882 (1) 1537bp
Genomic GenBank:CU639412 (1) 58624bp
Select Tool
Polypeptide UniProtKB:F1QCB2 (1) 360aa
Sequence Clusters UniGene:84258 (1)
Sequence Information (all 16)
ORTHOLOGY for cxcr4a (Chr: 6)
CITATIONS (90)