Gene

cp

ID
ZDB-GENE-010522-1
Name
ceruloplasmin
Symbol
cp Nomenclature History
Previous Names
  • cer (1)
  • wu:fi23f10 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have ferroxidase activity. Predicted to be involved in iron ion homeostasis and iron ion transport. Localizes to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Is expressed in digestive system; female organism; liver and biliary system; male organism; and yolk syncytial layer. Orthologous to human CP (ceruloplasmin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
84 figures from 53 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Choksi et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
aceruloplasminemia Alliance Cerebellar ataxia 604290
aceruloplasminemia Alliance Hemosiderosis, systemic, due to aceruloplasminemia 604290
aceruloplasminemia Alliance [Hypoceruloplasminemia, hereditary] 604290
Associated With cp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR002355 Multicopper oxidase, copper-binding site
Conserved_site IPR033138 Multicopper oxidases, conserved site
Domain IPR011706 Multicopper oxidase, type 2
Domain IPR011707 Multicopper oxidase, type 3
Homologous_superfamily IPR008972 Cupredoxin
Domain Details Per Protein
Protein Length Cupredoxin Multicopper oxidase, copper-binding site Multicopper oxidases, conserved site Multicopper oxidase, type 2 Multicopper oxidase, type 3
UniProtKB:Q6P3G1 1087
UniProtKB:Q7ZU12 1087
UniProtKB:F1Q8N4 194
UniProtKB:Q90ZT2 626
UniProtKB:F1RBQ0 193
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cp polyclonal Rabbit
  • WB
AnaSpec
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations