ZFIN ID: ZDB-GENE-010416-1
Gene Name: BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
Gene Symbol: bambia    Nomenclature History

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Previous Names: bambi, nma (1), cb998 (1), etID64300.12 (1), fc44c12 (1), id:ibd5020 (1), wu:fc44c12 (1), wu:fe01e03 (1), Zfnma (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have frizzled binding activity. Involved in dorsal/ventral pattern formation; negative regulation of BMP signaling pathway; and platelet activation. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; germ ring; optic cup; and pectoral fin bud. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human BAMBI (BMP and activin membrane bound inhibitor).
Genome Resources: Alliance (1),  Gene:83496 (1),  Ensembl(GRCz11):ENSDARG00000055381 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2630 Point Mutation Unknown Premature Stop ENU
sa35297 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-bambia N/A 1
    MO2-bambia N/A 1
    DISEASE ASSOCIATED WITH bambia HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bambia VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component integral component of plasma membrane (more)
    Molecular Function frizzled binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bambia-201 (1)    Ensembl 1569
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bambia No data available
    MARKER RELATIONSHIPS
    bambia Contained in: [BAC] CH211-112K3 (1)
    bambia Contains: [SNP] rs3728472 (1), rs3728473 (1), rs3728474 (1)
    bambia Encodes: [EST] cb998 (1) (order this), fc44c12, fe01e03 (1), ibd5020 (1), IMAGE:6910718 (1)
    [cDNA] MGC:73034 (1), MGC:86579 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131784 (1) 1564 nt
    Genomic GenBank:BX005058 (1) 170139 nt
    Select Tool
    Polypeptide UniProtKB:Q6IQW1 (1) 258 aa
    Sequence Information (all 24)
    ORTHOLOGY for bambia ( Chr: 12 )
    CITATIONS (51)