ZFIN ID: ZDB-GENE-010328-5
Gene Name: claudin e
Gene Symbol: cldne    Nomenclature History

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Previous Names: cb84 (1), fb16e12, wu:fb16e12 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have structural molecule activity. Involved in epiboly involved in gastrulation with mouth forming second. Predicted to localize to bicellular tight junction and plasma membrane. Is expressed in several structures, including EVL; blastomere; digestive system; ectoderm; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in ovarian cancer and pancreatic cancer. Orthologous to several human genes including CLDN4 (claudin 4).
Genome Resources: Alliance (1),  Gene:81584 (1),  Ensembl(GRCz11):ENSDARG00000043128 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-cldne N/A 1
MO2-cldne N/A 1
DISEASE ASSOCIATED WITH cldne HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cldne VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process epiboly involved in gastrulation with mouth forming second (more)
Cellular Component bicellular tight junction (more)
Molecular Function structural molecule activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cldne-201 (1)    Ensembl 2083
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cldne No data available
MARKER RELATIONSHIPS
cldne Contained in: [BAC] CH211-235M3 (1)
cldne Encodes: [EST] cb84 (1) (order this), fb16e12 (1) (order this)
[cDNA] MGC:77738 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131765 (1) 1955 nt
Genomic GenBank:CR382327 (1) 151282 nt
Select Tool
Polypeptide UniProtKB:Q90XR9 (1) 209 aa
Sequence Information (all 13)
ORTHOLOGY for cldne ( Chr: 15 )
CITATIONS (40)