ZFIN ID: ZDB-GENE-001212-1
Gene Name: ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 1
Gene Symbol: atp1a1a.1
Previous Names: atp1a1, atp[a]1B1 (1), cb70 (1), had (1), snk (1), heart and mind (1), snakehead (1), wu:fa03c03, wu:fb92h10 (1)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 29 figures from 12 publications
Directly Submitted Expression Data: 6 figures (19 images) from Rauch et al., 2003 [fb81h09]
  6 figures (22 images) from Thisse et al., 2001 [cb70]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
  adaxial cell, alar plate midbrain region, blastomere, brain (all 35) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi3475Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la1 Indel Splice Junction Splice Site SPONTANEOUS
    la028094Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m115 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m273 Unknown Unknown Unknown ENU
    m291 Unknown Unknown Unknown
    m523 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m883 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • mw15b Small Deletion Exon 17 - Intron 17 Splice Junction Splice Site ENU
    sa12184 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13646 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa15598 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa19398 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tj223 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tl30 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm52 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • to273a Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tu236 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tw3b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: CRISPR1-atp1a1a.1 (2), MO1-atp1a1a.1 (1), MO2-atp1a1a.1 (1), MO3-atp1a1a.1 (1)
    PHENOTYPE
    Data: 31 figures from 10 publications
    Observed in: anatomical system, blood circulation, brain, cell migration involved in heart formation (all 39) expand
    DISEASE ASSOCIATED WITH atp1a1a.1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process otolith development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function sodium:potassium-exchanging ATPase activity (more)
    GO Terms (all 35)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005775 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • Pfam:PF08282 (1)
  • EC:3.6.3.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp1a1a.1-001 (1) 3506
    ncRNA atp1a1a.1-002 (1) 867
    atp1a1a.1-003 (1) 416
    atp1a1a.1-004 (1) 313
    atp1a1a.1-005 (1) 652
    atp1a1a.1-006 (1) 772
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIES
    Ab3-atp1a1 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM atp1a1a.1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atp1a1a.1Contained in: [BAC] DKEY-208K14 (1) (order this)
    atp1a1a.1Encodes: [EST] cb70 (1) (order this), fa03c03 (1), fb81h09 (1) (order this), fb92h10 (1)
    [cDNA] MGC:55250 (1) (order this), MGC:77580 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131686 (1) 3497bp
    Genomic GenBank:CU185242 (1) 180192bp
    Select Tool
    Polypeptide UniProtKB:Q7ZU25 (1) 1028aa
    Sequence Clusters UniGene:75307 (1)
    Sequence Information (all 26)
    OTHER atp1a1a.1 GENE PAGES
  • Gene:64612 (1)
  • VEGA:OTTDARG00000029782 (1)
  • Ensembl(GRCz10):ENSDARG00000002791 (1)
  • ORTHOLOGY for atp1a1a.1 (Chr: 1)
    Species Symbol Chromosome Accession # Evidence
    Human ATP1A1 1
  • Gene:476
  • OMIM:182310
  • HGNC:799
  • Amino acid sequence comparison (5)
    Conserved genome location (synteny) (2)
    Mouse Atp1a1 3
  • MGI:88105
  • Gene:11928
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (61)