ZFIN ID: ZDB-GENE-001120-1
Gene Name: LIM domain and actin binding 1a
Gene Symbol: lima1a    Nomenclature History

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Previous Names: lima1, cb1006 (1), eplin (1), wu:fd15g06 (1), wu:fd20b10 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to localize to actin cytoskeleton and plasma membrane. Is expressed in several structures, including blood vessel; hindbrain neural plate; midbrain neural keel; nervous system; and periderm. Orthologous to human LIMA1 (LIM domain and actin binding 1).
Genome Resources: Alliance (1),  Gene:64000 (1),  Ensembl(GRCz11):ENSDARG00000101441 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010027Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011292Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022714Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028563Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028564Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14742 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39425 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tud39Gt Transgenic Insertion Intron 2 Unknown DNA
    PHENOTYPE
    Data: Fig. 3 from Jungke et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH lima1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    [Low density lipoprotein cholesterol level QTL 8] 618079
    DISEASE ASSOCIATED WITH lima1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament bundle assembly (more)
    Cellular Component actin cytoskeleton (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM lima1a No data available
    MARKER RELATIONSHIPS
    lima1a Encodes: [EST] cb1006 (1) (order this), fd15g06 (1), fd20b10 (1)
    [cDNA] MGC:55222 (1), MGC:191969 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131664 (1)
    Polypeptide UniProtKB:Q7ZU52 (1) 629 aa
    Sequence Information (all 21)
    ORTHOLOGY for lima1a ( Chr: 23 )
    CITATIONS (27)