FIGURE

Figure 6

ID

ZDB-FIG-240617-39

Publication

Zhang et al., 2024 - Lactobacillus rhamnosus GG triggers intestinal epithelium injury in zebrafish revealing host dependent beneficial effects

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Figure 6

Illustration of the mechanisms underlying the activation of SpaC to intestinal pyroptosis. The SpaC pilin of LGG induces intestinal epithelium injury through a species‐specific activation of TLR4ba, which initiates Caspase‐3−GSDMEa pyroptosis and secondarily activates Gaspy2−GSDMEb pyroptosis via gut microbiota dysbiosis.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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