FIGURE

FIGURE 6

ID
ZDB-FIG-240327-19
Publication
Utsumi et al., 2024 - Deficiency of mastl, a mitotic regulator, results in cell detachment from developing tissues of zebrafish embryos
Other Figures
All Figure Page
Back to All Figure Page
FIGURE 6

Decondensation of chromosomes and re-expression of foxa2 in detached cells in mastlkt441b homozygous embryos. Classification of cells detached from the CNH by foxa2 expression and chromosome condensation in mastlkt441b homozygous embryos carrying Bac(foxa2/Kaede) transgene at 8 ss, 12 ss and 16 ss. In situ hybridization of foxa2 mRNA and immunostaining with anti-Kaede antibody was carried out. Kaede-positive cells, i.e., cells detached from the CNH, in 4 mastlkt441b homozygous embryos are classified according to foxa2 mRNA expression and chromosome condensation. Note that most foxa2-expressing cells had decondensed chromosomes, suggesting that foxa2 expression was restarted after completion of mitosis.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol