FIGURE
Fig. 1
- ID
- ZDB-FIG-230925-10
- Publication
- Dal Forno et al., 2023 - Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C-C Bond Cleavage Reactions
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Fig. 1
Palladium-mediated bioorthogonal bond cleavage strategies. (A) Palladium-mediated N/O-deallylation and depropargylation reactions for the activation of masked small molecules, proteins, and bioconjugates. (B) Specific enzymatic trigger, an acid-promoted, self-immolative C–C bond-cleaving 1,6-elimination mechanism releases β-lapachone.30 (C) This work, the decaging of the prodrug propargyl β-lapachone, through a palladium(II) nanoparticles-mediated C–C bond cleavage. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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