Figure 6—figure supplement 4.

Semi-quantitative qPCR analyses comparing expression of known p53 direct regulated genes baxa, bbc3, cdkn1a, gadd45a, and noxa in primary zebrafish embryonal rhabdomyosarcoma (ERMS) expressing wt tp53 (blue, n = 3), tp53-/- (red, n = 3), and tp53-/- + TP53Y220C (green, n = 3).

Also shown is expression of zebrafish tp53 across the tumors. The wt and tp53-/- tumors are the same controls from Figure 4—figure supplement 3.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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