FIGURE

Fig. 3

ID
ZDB-FIG-230508-94
Publication
Lasbleiz et al., 2022 - Sigma-1 receptor agonist PRE-084 confers protection against TAR DNA-binding protein-43 toxicity through NRF2 signalling
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Fig. 3

PRE-84 boosted maximal mitochondrial respiration of TDP43G348C-expressing larvae. (A) Oxygen consumption rate (OCR) was measured using the Seahorse system on control and TDP43G348C larvae. (B) Basal mitochondrial respiration, maximal capacity of mitochondrial respiration and non-mitochondrial respiration were measured on control and TDP43G348C larvae treated or not with PRE-084. Data from n = 18–33 larvae were presented as mean ± SEM. Statistical analysis was performed by the Student t-test (*p < 0.05; **p < 0.01).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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