FIGURE
Fig. 6
- ID
- ZDB-FIG-230508-100
- Publication
- Lasbleiz et al., 2022 - Sigma-1 receptor agonist PRE-084 confers protection against TAR DNA-binding protein-43 toxicity through NRF2 signalling
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Fig. 6
PRE-084 boosted NRF2 signalling cascade and alleviates TDP43G348C toxicity. (A and B) RNA expression levels of NRF2 and its targets: GCLC, GCLM, PRDX6 and PGD in TDP43G348C larvae treated or not with PRE-084 after an ER stress induction with tunicamycin for 24 h (A) or 2 h (B). Data from n = 8–9 (24 h) and n = 6–7 (2 h) were presented as mean ± SEM. Statistical analysis was performed by the Student t-test (*p < 0.05; **p < 0.01; ***p < 0.001). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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