Figure 7

Blocking Cb1r and Cb2r activity prevents the CBN-induced changes in hair cell development along the pLL. (A) Images are taken along the pLL at ×500 magnification for 3 mg L⁻¹ CBN (n = 5), AM251 10 nm + 3 mg L⁻¹ CBN (n = 5), AM630 10 µm + 3 mg L⁻¹ CBN (n = 5) and AM251 10 nm + AM630 10 µm + 3 mg L⁻¹ CBN (n = 5). Scale bar represents 100 µm for the top row. N = 3 experiments. The bottom row shows higher magnification images of the pLL (×10,000 magnification). Scale bar represents 5 µm. (I) Bar graph showing the quantification of the percentage of the embryos that exhibited deformities in their hair cell along pLL. N = 3 experiments. Groups which share the same letter(s) of the alphabet are not statistically different from one another; p < 0.05.