FIGURE

Fig. 5

ID

ZDB-FIG-221004-15

Publication

Ncube et al., 2022 - A conserved transcriptional fingerprint of multi-neurotransmitter neurons necessary for social behavior

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Fig. 5

vTel^y321 “transcriptomic fingerprint” is evolutionarily conserved. A Single cell RNA-sequencing data from Atlas of Zebrafish Development plotted using Uniform Manifold Approximation and Projection (UMAP) algorithm. The atlas consists of 220 computationally identified clusters and each of the clusters were annotated using cell-type information from previously identified marker genes from the Zebrafish Information Network (ZIFN). B “Transcriptomic fingerprint” expressed genes map onto Cluster 25 of the Atlas and their expression is plotted in UMAP space. Vgat expression in Cluster 25 included as a corroboratory marker. C Search results from the mousebrain.org online scRNAseq Atlas show that combined expression of Lhx6, Isl1, Lhx8, Gad1 and Chat maps onto telencephalic (TECHO) and diencephalic (DECHO1) clusters in the mouse brain. Other cholinergic clusters HBCHO1–4, MBCHO4, and DECHO2 do not express the full transcriptomic fingerprint

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Genomics