FIGURE

Fig. 6

ID
ZDB-FIG-220620-38
Publication
Wang et al., 2020 - RNA-based therapies in animal models of Leber congenital amaurosis causing blindness
Other Figures
All Figure Page
Back to All Figure Page
Fig. 6

UPF1 phosphorylation in mouse Rd12 retina/RPE extracts analyzed by western blotting. (A) UPF1 protein expression in wildtype (Wt), untreated Rd12 mutants (Mt), Mt treated postnatally (Mt Post), and Mt treated prenatally plus postnatal treatment (Mt Pre). UPF1 is seen as a doublet on western blotting. (B) Phosphorylated UPF1 (p-UPF1) in Wt, Mt, Mt Post, and Mt Pre protein extracts. (C) β-actin loading control. Protein marker is BLUelf ladder. (D) Quantification of p-UPF1 expression between treatment groups relative to β-actin. Untreated Mt set as 100% p-UPF1expression level.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Precis Clin Med