FIGURE

Figure 4—figure supplement 2.

ID

ZDB-FIG-220314-80

Publication

Qi et al., 2022 - Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish

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Figure 4—figure supplement 2.

Apelin signaling regulates cardiomyocyte (CM) proliferation in the ventricle.

(A–D) Confocal projection images of the heart of Tg(myl7:HsHRAS-EGFP) larvae at 72 hours post-fertilization (hpf). (A–B) Maximum intensity projections of confocal images. (C–D) Mid-sagittal sections of A and B, respectively. apln^-/- larvae (D) exhibit fewer EdU⁺ CMs (arrows) in their ventricle compared with apln^+/+ siblings (C). (E) Quantification of the percentage of EdU⁺ CMs in the ventricle of apln^+/+ and apln^-/- siblings. V, ventricle. Data in graphs expressed as mean ± SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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