FIGURE

Fig. 3

ID

ZDB-FIG-220203-91

Publication

Missinato et al., 2021 - Zebrafish heart regenerates after chemoptogenetic cardiomyocyte depletion

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Fig. 3

Myocardium integrity was reduced after MG-2I treatment. Fluorescent in situ hybridization was used to assess the integrity of the myocardium after different types of injury. A representative image of uninjured heart (A–D; n = 5), 3 dpa (E–H; n = 3), control PBS treated Tg(myl7:fapdl1-cerulean) at 3 dpi (I–L and U, U′; n = 4), MG-2I treated Tg(myl7:fapdl1-cerulean) at 3 dpi (M–P and V, V′; n = 3) and 5 dpi (Q–T and W, W′; n = 4) are shown. Uniform distribution of myl7 were noted in uninjured and PBS control treated hearts at 3 dpi (A–D and E–H). Absence of myl7 were detected in 3 dpi (M–P, V) and 5 dpi (Q–T, W) hearts treated with MG-2I and infrared light that indicated loss of trabeculated myocardium and damage to the compact myocardium as marked by asterisks. Scale bar = 50 μm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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