FIGURE

Fig. 6

ID

ZDB-FIG-210311-14

Publication

Castellanos et al., 2021 - Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish

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Fig. 6

The number of Sox10⁺ cells is decreased in morphants at 4 DPF. a-bTg(sox10:TagRFP) random control (RC) and morphant (MO) larvae (N = 10 per group) were mounted in agarose and confocal images were taken at 4 days post fertilization (DPF). c shows the representative region where cells were quantified with a corresponding schematic showing the parameters (3 rows left, 5 rows right). c′ Average number of Sox10⁺ cells counted across both groups N = 10 per group) at 4 DPF. P-value pertains to the statistically significant difference between the RC group and the MO group (***p = 0.0002). d qPCR demonstrating the expression of sox10 (N = 15 total) in RC and MO groups at 4 DPF (**p = 0.005). qPCR was performed on two independent occasions (biological replicates), each represented by a gray dot. Each biological replicate had a minimum of 7 larvae/group and a total n = 15

Expression Data

Genes:	sox10 TagRFP
Fish:	co26Tg + MO4-hspg2
Knockdown Reagent:	MO4-hspg2
Anatomical Terms:	chondrocyte whole organism
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	co26Tg + MO4-hspg2
Knockdown Reagent:	MO4-hspg2
Observed In:	chondrocyte cranial neural crest neural crest cell differentiation whole organism
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.