FIGURE

FIGURE 3

ID

ZDB-FIG-210125-9

Publication

Li et al., 2020 - Naringin attenuates cisplatin- and aminoglycoside-induced hair cell injury in the zebrafish lateral line via multiple pathways

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FIGURE 3

Nar protects against neomycin ototoxicity. (A) Animals were fixed and immunostained for MyosinVIIa (green), and DAPI. 5 dpf zebrafish were incubated with 0 μmol/L to 150 μmol/L Neo for 1 h, or pre‐treated with 0 µmol/L to 400 µmol/L of Nar for 3 h and then co‐treated with Nar and Neo (100 µmol/L) for 3 h. (B) Diagram of the assay for A. (C and D) Quantification of the number of hair cells (MyosinVIIa⁺) per neuromast after the different treatments represented as mean ± SEM (n = 10). Control animals were exposed to vehicle alone (DMSO). ***P < 0.001. Black asterisks compared to DMSO‐treated animals. Red asterisks compared versus the corresponding Neo concentration. (E) Scares for neuromast morphology of each group(see Materials and Methods). Scale bar equals 5 μm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell. Mol. Med.