ZFIN ID: ZDB-FIG-190925-32
Hitzel et al., 2018 - Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Nature communications   9:2292 Full text @ Nat. Commun.
EXPRESSION / LABELING:
Gene:
Fish:
Condition:
Anatomical Term:
Stage: Protruding-mouth
PHENOTYPE:
Fish:
Condition:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
mthfd2 y1Tg chemical treatment by injection: oxidised phospholipid Protruding-mouth whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
y1Tg chemical treatment by injection: oxidised phospholipid Protruding-mouth intersegmental vessel increased branchiness, abnormal
Protruding-mouth intersegmental vessel morphology, abnormal
Protruding-mouth whole organism mthfd2 expression increased amount, abnormal
y1Tg + MO1-mthfd2 chemical treatment by injection: oxidised phospholipid Protruding-mouth intersegmental vessel increased branchiness, abnormal
Protruding-mouth intersegmental vessel morphology, abnormal
Full text @ Nat. Commun.