FIGURE

Figure 2

ID

ZDB-FIG-190723-1991

Publication

Jo et al., 2013 - Animal models of diabetic retinopathy: doors to investigate pathogenesis and potential therapeutics

Other Figures

All Figure Page

Back to All Figure Page

Figure 2

Animal models of DR demonstrating increased vascular permeability (A) and retinal neovascularization (B). (A) Intraperitoneal injection of streptozocin to mice leads to hyperglycemia in 2 ~ 3 days and increased vascular permeability ensues in a week. Flat-mounted retina after the intravenous injection of FITC-dextran evidences diffuse leakage of retinal vessels. (B) Exposure to hyperoxia from P7 to P12 results in retinal neovascularization, which starts at P14 and peaks at P17. Flat-mounted retina after the intravenous injection of FITC-dextran demonstrates central ischemic retina with small vascular tufts at the junction between vascularized and avascular retina.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Biomed. Sci.