ZFIN ID: ZDB-FIG-190722-25
Delacruz et al., 2019 - Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas. Oncotarget   10:3939-3951 Full text @ Oncotarget
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Long-pec to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Fig. 2

CNOT3 is required for intestinal differentiation. WISH staining for (A) the gut precursor marker gata6 (pg) at 48 hpf and (B) the differentiated gut-specific marker fabp2 (g) in 72 and 96 hpf control and cnot3a morphants.

 

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
fabp2 TU standard conditions Protruding-mouth gut ISH
TU + MO1-cnot3a standard conditions Protruding-mouth gut ISH
gata6 TU standard conditions Long-pec intestinal bulb ISH
TU + MO1-cnot3a standard conditions Long-pec intestinal bulb ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TU + MO1-cnot3a standard conditions Protruding-mouth gut fabp2 expression decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Oncotarget for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Oncotarget