ZFIN ID: ZDB-GENE-991019-5
Gene Name: fatty acid binding protein 2, intestinal
Gene Symbol: fabp2    Nomenclature History

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Previous Names: I-FABP, ifabp, intestinal fatty acid binding protein, zgc:92264

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have fatty acid binding activity. Involved in response to lipid. Is expressed in brain; gut; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in alcoholic liver cirrhosis; carotid stenosis; coronary artery disease; end stage renal disease; and obesity. Orthologous to human FABP2 (fatty acid binding protein 2).
Genome Resources: Alliance (1),  Gene:30708 (1),  Ensembl(GRCz11):ENSDARG00000006427 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zko497a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fabp2
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fabp2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fabp2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to lipid (more)
    Molecular Function fatty acid binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fabp2-201 (1)    Ensembl 1066
    ncRNA fabp2-002 (1)    Ensembl 544
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-fabp2 polyclonal Rabbit IHC 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fabp2
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-4.5fabp2:DsRed) fabp2 DsRed Danio rerio 1 8
    tg(fabp2:apoa1a-mcherry) fabp2 apoa1amCherry Danio rerio 1 1
    Tg(fabp2:DsRed) fabp2 DsRed Danio rerio 1 4
    Tg(fabp2:EGFP) fabp2 EGFP Danio rerio 1 2
    Tg(fabp2:EGFP-acsl3a) fabp2 acsl3aEGFP Danio rerio 1 2
    Tg(fabp2:EGFP-CAAX) fabp2 EGFP Danio rerio 1 2
    Tg(fabp2:EGFP-nr1h3) fabp2 EGFPnr1h3 Danio rerio 1 4
    Tg(fabp2:GFP) fabp2 GFP Danio rerio 1 6
    Tg(fabp2:Hpy.CagA-EGFP) fabp2 EGFP Danio rerioHelicobacter plylori 1 3
    tg(fabp2:hsa.apoa1-mcherry) fabp2 mCherry Danio rerioHomo sapiens 1 1
    Tg(fabp2:Hsa.RPIA,myl7:EGFP) fabp2myl7 EGFP Danio rerioHomo sapiens 1 1
    tg(fabp2:lexpr,lexop:egfp-krasg12v) fabp2LEXOP EGFPkrasLEXPR Danio rerio 1 2
    Tg(fabp2:NLS-mCherry,fli1:iRFP) fabp2fli1 mCherryNLSRFP Danio rerio 1 1
    Tg(fabp2:RFP) fabp2 RFP Danio rerio 1 8
    tg(fabp2:sec-rfp) fabp2 RFPSEC Danio rerio 1 1
    tg(fabp2:tdtomato-2a-dnxla.rbpj) fabp2 2ATomato Danio rerioXenopus laevis 1 1
    Tg2(fabp2:DsRed) fabp2 DsRed Danio rerio 1 1
    MARKER RELATIONSHIPS
    fabp2 Contained in: [BAC] CH73-34B5 (1)
    fabp2 Encodes: [cDNA] MGC:92264 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131431 (1) 645 nt
    Genomic GenBank:CU571168 (1) 111328 nt
    Select Tool
    Polypeptide UniProtKB:Q8AX65 (1) 132 aa
    Sequence Information (all 19)
    ORTHOLOGY for fabp2 ( Chr: 1 )
    CITATIONS (138)