FIGURE

Fig. 3

ID

ZDB-FIG-190626-57

Publication

Chrispell et al., 2018 - Grk1b and Grk7a Both Contribute to the Recovery of the Isolated Cone Photoresponse in Larval Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Electrophysiological light responses and normalized sensitivity of grk1b and grk7a knockout larvae. (A) Representative ERG traces of isolated cone-mass receptor potentials in APB-treated larvae at 5 dpf. Reponses were recorded under dark-adapted conditions to 20-ms flashes of light of increasing intensities equal to 0.1, 1, 10, 25, 50, 125, 250, 500, 1250, 2500, and 5000 cd/m². The fast initial positive deflection can be attributed to a photovoltaic effect with the recording microelectrode. (B) Peak amplitude responses of 5 dpf larvae fit using the Naka-Rushton function. (C) Mean-normalized peak response amplitudes of 5 dpf larvae fit using the Naka-Rushton function. Error bars represent SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	grk1b^nc201/nc201 grk7a^nc200/nc200
Observed In:	retinal cone cell detection of light stimulus involved in visual perception
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.