FIGURE

Fig. 3

ID

ZDB-FIG-190218-3

Publication

Kong et al., 2018 - Generation of motor neurons requires spatiotemporal coordination between retinoic acid and Mib-mediated Notch signaling

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Fig. 3

Retinoid pathway attenuates the effect of overexpression of Mib:EGFP. Lateral views. Anterior to the left. At 26 hpf, expression of islet1 between the 8th and 11th somites of embryos following no treatment (A–C), retinoic acid (RA) treatment (A’ and B’) or citral treatment (C and C’). Wild-type (A, A’ and C) and Tg[hsp70-mib:EGFP] (B, B’ and C’) embryos were heat-shocked at the 14-somite stage (ss). Motor neuron (MN) clusters (brackets) located in the somites flanking non-MN domain in wild-type embryos. Ectopic motor neurons (arrows) filled the gaps between motor neuron clusters (brackets) in Tg[hsp70-mib:EGFP] embryos following heat-shock at the 14ss (B) and exposure to citral at the 14ss (C’). Scale bar: 100 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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