FIGURE

Fig. 1

ID

ZDB-FIG-190118-10

Publication

Alzualde et al., 2018 - Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human relevance

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Fig. 1

Developmental Toxicity assay and examples of the results obtained for the some of the BFRs and OPFRs (Experiment 1). A) Schematic depicting a summary of the experimental design of developmental toxicity assay. B, C, D) Results obtained for the BFR TBBPA (B) and for the replacement OPFRs IPP (C) and TDCIPP (D). Sigmoidal dose-response curves were calculated at 2 and 4 dpf for the percentage of affected and dead embryos. TI values (LC50/EC50) are indicated. Representative bright field pictures of the embryos treated at the stages and concentrations indicated are also shown. Asterisks point to the absence of eyes. Scale bar, 200 μM in all pictures.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neurotoxicol. Teratol.