ZFIN ID: ZDB-FIG-170517-49
Utami et al., 2014 - Impaired Development Of Neural-Crest Cell Derived Organs and Intellectual Disability Caused By MED13L Haploinsufficiency. Human Mutation   35(11):1311-20 Full text @ Hum. Mutat.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Prim-5 to Long-pec
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-5 to Day 5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
EGFP knu3Tg control Long-pec neuron IFL
Long-pec optic tectum IFL
knu3Tg + MO2-med13b standard conditions Long-pec neuron IFL
Long-pec optic tectum IFL
isl1a AB control Long-pec hypothalamus ISH
Long-pec retinal ganglion cell ISH
Long-pec ventral telencephalon ISH
AB + MO2-med13b standard conditions Long-pec hypothalamus ISH
Long-pec Not Detected retinal ganglion cell ISH
Long-pec ventral telencephalon ISH
sox10 AB control Prim-5 cranial neural crest cell ISH
AB + MO2-med13b standard conditions Prim-5 cranial neural crest cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO2-med13b standard conditions Prim-5 cranial neural crest cell sox10 expression mislocalised, abnormal
Prim-5 cranial neural crest cell mislocalised, abnormal
Prim-5 neural crest cell migration decreased process quality, abnormal
Long-pec hypothalamus isl1a expression decreased amount, abnormal
Long-pec retinal ganglion cell isl1a expression absent, abnormal
Long-pec ventral telencephalon isl1a expression decreased amount, abnormal
Day 5 ceratohyal cartilage deformed, abnormal
Day 5 ceratohyal cartilage mislocalised posteriorly, abnormal
knu3Tg + MO2-med13b standard conditions Long-pec nervous system development disrupted, abnormal
Long-pec optic tectum EGFP expression decreased amount, abnormal
Full text @ Hum. Mutat.
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