header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-160920-6
Li et al., 2016 - Alcohol exposure leads to unrecoverable cardiovascular defects along with edema and motor function changes in developing zebrafish larvae. Biology Open   5(8):1128-33 Full text @ Biol. Open
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Condition:
Anatomical Terms:
Stage: Day 6
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Day 6

Fig. 3

Morphology, histopathological examination and vascular structure in ethanol-treated and untreated larvae. (A-C) Morphological characteristics of ethanol-treated and untreated larvae at 6dpf. (D-I) H&E staining of transverse sections at site of abdomen in untreated and ethanol-treated larvae. Boxed areas in D,F,H magnified in E,G,I. (J,L,N) Reconstructed images of vascular structure in untreated and ethanol-treated larvae by confocal imaging. (K,M,O) Tomography of vascular structure in control and alcohol-treated larvae by confocal imaging. Asterisk in N,O indicates destruction in dorsal aorta.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP y1Tg control Day 6 dorsal aorta IFL
Day 6 trunk vasculature blood vessel IFL
y1Tg chemical treatment by environment: ethanol Day 6 dorsal aorta IFL
Day 6 trunk vasculature blood vessel IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB chemical treatment by environment: ethanol Day 6 muscle structure, abnormal
Day 6 pericardium edematous, abnormal
y1Tg chemical treatment by environment: ethanol Day 6 dorsal aorta broken, abnormal
Day 6 intersegmental artery morphology, abnormal
Day 6 trunk vasculature blood vessel broken, abnormal
Day 6 trunk vasculature blood vessel morphology, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Biology Open for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Biol. Open