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General Information
ZIRC
ZFIN ID: ZDB-FIG-160817-31
Reischauer et al., 2016 - Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Nature   535:294-8 Full text @ Nature
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: 1-4 somites to Prim-5
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: 1-4 somites to Prim-5

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP npas4lbns59/+; s843Tg standard conditions Prim-5 caudal vein plexus IFL
Prim-5 intersegmental vessel IFL
npas4lbns59/bns59; s843Tg standard conditions Prim-5 caudal vein plexus IFL
Prim-5 intersegmental vessel IFL
npas4ls5/+; npas4lbns59/+; s843Tg standard conditions Prim-5 caudal vein plexus IFL
Prim-5 intersegmental vessel IFL
npas4ls5/s5; s843Tg standard conditions Prim-5 caudal vein plexus IFL
Prim-5 intersegmental vessel IFL
s843Tg + MO1-npas4l + MO2-npas4l standard conditions Prim-5 caudal vein plexus IFL
Prim-5 intersegmental vessel IFL
etsrp WT standard conditions 1-4 somites posterior lateral mesoderm ISH
14-19 somites posterior lateral plate mesoderm ISH
14-19 somites tail bud ISH
npas4lbns59/bns59 standard conditions 1-4 somites posterior lateral mesoderm ISH
14-19 somites posterior lateral plate mesoderm ISH
14-19 somites tail bud ISH
tal1 WT standard conditions 1-4 somites posterior lateral mesoderm ISH
14-19 somites posterior lateral plate mesoderm ISH
14-19 somites tail bud ISH
npas4lbns59/bns59 standard conditions 1-4 somites posterior lateral mesoderm ISH
14-19 somites posterior lateral plate mesoderm ISH
14-19 somites tail bud ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
npas4lbns59/bns59 standard conditions 1-4 somites lateral plate mesoderm decreased size, abnormal
1-4 somites posterior lateral mesoderm etsrp expression decreased amount, abnormal
1-4 somites posterior lateral mesoderm tal1 expression decreased amount, abnormal
14-19 somites intermediate cell mass of mesoderm decreased size, abnormal
14-19 somites posterior lateral plate mesoderm etsrp expression decreased amount, abnormal
14-19 somites posterior lateral plate mesoderm tal1 expression decreased amount, abnormal
14-19 somites posterior lateral plate mesoderm tal1 expression decreased distribution, abnormal
14-19 somites posterior lateral plate mesoderm etsrp expression decreased distribution, abnormal
npas4lbns59/bns59; s843Tg standard conditions Prim-5 blood vasculature lacks parts or has fewer parts of type blood vessel, abnormal
Prim-5 caudal vein plexus EGFP expression decreased amount, abnormal
Prim-5 intersegmental vessel EGFP expression decreased amount, abnormal
npas4ls5/+; npas4lbns59/+; s843Tg standard conditions Prim-5 blood vasculature lacks parts or has fewer parts of type blood vessel, abnormal
Prim-5 caudal vein plexus EGFP expression decreased amount, abnormal
Prim-5 intersegmental vessel EGFP expression decreased amount, abnormal
npas4ls5/s5; s843Tg standard conditions Prim-5 blood vasculature lacks parts or has fewer parts of type blood vessel, abnormal
Prim-5 caudal vein plexus EGFP expression decreased amount, abnormal
Prim-5 intersegmental vessel EGFP expression decreased amount, abnormal
s843Tg + MO1-npas4l + MO2-npas4l standard conditions Prim-5 blood vasculature lacks parts or has fewer parts of type blood vessel, abnormal
Prim-5 caudal vein plexus EGFP expression decreased amount, abnormal
Prim-5 intersegmental vessel EGFP expression decreased amount, abnormal
Full text @ Nature