header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-160517-50
Marchegiani et al., 2015 - Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes. American journal of human genetics   97(1):99-110 Full text @ Am. J. Hum. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Term:
Stage Range: 75%-epiboly to 1-4 somites
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: 75%-epiboly to Prim-5

Fig. S3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
efemp2b zf599Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
zf600Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
fgl2a zf599Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
zf600Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
fmoda zf599Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
zf600Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
gfra3 zf599Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
zf600Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
p3h3 zf599Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
zf600Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
pdgfra zf599Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
zf600Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
si:ch211-216b21.2 zf599Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
zf600Tg ; zf602Tg heat shock 75%-epiboly to 1-4 somites whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
zf599Tg ; zf602Tg standard conditions Prim-5 brain hypoplastic, abnormal
Prim-5 head hypoplastic, abnormal
Prim-5 midbrain hindbrain boundary morphology, abnormal
Prim-5 pericardium edematous, abnormal
Prim-5 trunk morphology, abnormal
zf599Tg ; zf602Tg heat shock 75%-epiboly - 1-4 somites whole organism p3h3 expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism si:ch211-216b21.2 expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism fgl2a expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism fmoda expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism gfra3 expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism efemp2b expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism pdgfra expression decreased amount, abnormal
zf600Tg ; zf602Tg standard conditions Prim-5 brain hypoplastic, abnormal
Prim-5 head hypoplastic, abnormal
Prim-5 midbrain hindbrain boundary morphology, abnormal
Prim-5 pericardium edematous, abnormal
Prim-5 trunk morphology, abnormal
zf600Tg ; zf602Tg heat shock 75%-epiboly - 1-4 somites whole organism efemp2b expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism pdgfra expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism si:ch211-216b21.2 expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism p3h3 expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism gfra3 expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism fmoda expression decreased amount, abnormal
75%-epiboly - 1-4 somites whole organism fgl2a expression increased amount, abnormal
zf601Tg ; zf602Tg standard conditions Prim-5 brain decreased size, abnormal
Full text @ Am. J. Hum. Genet.