ZFIN ID: ZDB-GENE-990415-208
Gene Name: platelet-derived growth factor receptor, alpha polypeptide
Gene Symbol: pdgfra
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: pdgfr-a (1), etID309717.20 (1), wu:fc27f02, wu:fv91b12

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 22 figures from 12 publications
Directly Submitted Expression Data: 6 figures (32 images) from Thisse et al., 2008 [cssl:d115]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b1059 Point Mutation Unknown Missense ENU
la021462Tg Transgenic Insertion Unknown Unknown DNA
sa271 Point Mutation Unknown Premature Stop ENU
sa29348 Point Mutation Unknown Premature Stop ENU
sa43427 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43428 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sk16 Point Mutation Intron 15 Splice Site, Exon Loss of Exon 14, Frameshift, Premature Stop ENU
    smh1300Gt Transgenic Insertion Intron 16 Unknown DNA
    Targeting reagents:
    PHENOTYPE
    Data: 22 figures from 6 publications
    Observed in:
    DISEASE ASSOCIATED WITH pdgfra HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    gastrointestinal stromal tumor Gastrointestinal stromal tumor, somatic 606764
    Hypereosinophilic syndrome, idiopathic, resistant to imatinib 607685
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cerebellum vasculature development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 26)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR001824 (1)
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020635 (1)
  • InterPro:IPR027290 (1)
  • InterPro:IPR036179 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS00240 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF07679 (1)
  • Pfam:PF07714 (1)
  • EC:2.7.10.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pdgfra-002 (1) 6274
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pdgfra No data available
    MARKER RELATIONSHIPS
    pdgfraContained in: [BAC] CH211-176L11 (1) (order this), DKEY-97C6 (1) (order this)
    pdgfraEncodes: [EST] fc27f02, fv91b12
    [cDNA] cssl:d115 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131459 (1) 3788bp
    Genomic GenBank:BX276097 (1) 216655bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QNY7 (1) 1456aa
    Sequence Clusters UniGene:75077 (1)
    Sequence Information (all 28)
    OTHER pdgfra GENE PAGES
  • Alliance (1)
  • Gene:386856 (1)
  • VEGA:OTTDARG00000033821 (1)
  • Ensembl(GRCz10):ENSDARG00000070494 (1)
  • ORTHOLOGY for pdgfra (Chr: 20)
    CITATIONS (52)