ZFIN ID: ZDB-GENE-110512-1
Gene Name: GDNF family receptor alpha 3
Gene Symbol: gfra3    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have signaling receptor activity. Involved in branchiomeric skeletal muscle development. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in hyoid muscle; pharyngeal arch; pharyngeal arch 1; pharyngeal arch 2; and pharyngeal musculature. Orthologous to human GFRA3 (GDNF family receptor alpha 3).
Genome Resources: Alliance (1),  Gene:556647 (1),  Ensembl(GRCz11):ENSDARG00000087704 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hh024 Point Mutation Intron 3 - Exon 4 Splice Junction Cryptic Acceptor Splice Site, Frameshift, Premature Stop
sa35633 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-gfra3 N/A 1
    MO2-gfra3 N/A 1
    DISEASE ASSOCIATED WITH gfra3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gfra3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process branchiomeric skeletal muscle development (more)
    Cellular Component external side of plasma membrane (more)
    Molecular Function signaling receptor activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gfra3-201 (1)    Ensembl 3619
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gfra3 No data available
    MARKER RELATIONSHIPS
    gfra3 Contained in: [BAC] CH211-235C4
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001256636 (1) 2112 nt
    Genomic GenBank:BX890575 (1) 204730 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E7F4G1 (1) 458 aa
    Sequence Information (all 8)
    ORTHOLOGY for gfra3 ( Chr: 14 )
    CITATIONS (22)