ZFIN ID: ZDB-FIG-160112-1
Zang et al., 2015 - Recoverin depletion accelerates cone photoresponse recovery. Open Biology   5(8) Full text @ Open Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 5

Fig. 3

Cone photoresponse recovery is accelerated in Rcv-deficient larvae. Time course of b-wave recovery in (a,b) UV spectral ERG, (c) maximum white light ERG and (d) dim white light ERG are shown. Under UV light conditions recoverin2a and combination of recoverin1a and recoverin2a are effective in accelerating the response recovery (a), whereas depleting the effort kinase Grk7a as expected prolongs the recovery time (b). Note that Rcv2a knockdown accelerates response recovery under normal and dim white light conditions, whereas Rcv2b only accelerates recovery under dim light conditions (c,d). Data are presented as mean ± s.e.m.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WIK + MO1-grk7a standard conditions Day 5 cone photoresponse recovery decreased efficacy, abnormal
WIK + MO1-rcvrn2 standard conditions Day 5 cone photoresponse recovery increased efficacy, abnormal
WIK + MO1-rcvrn2 + MO1-rcvrna standard conditions Day 5 cone photoresponse recovery increased efficacy, abnormal
WIK + MO1-rcvrn3 standard conditions Prim-5 cone photoresponse recovery increased efficacy, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Open Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Open Biol.