FIGURE

Fig. 6

ID

ZDB-FIG-150929-41

Publication

Rajaram et al., 2014 - Technical brief: Constant intense light exposure to lesion and initiate regeneration in normally pigmented zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Light treatment of pigmented retinas stimulates proliferation of MG and progenitor cells. tg:GFAP:GFP fish were exposed to intense light for 35 h (A) or 51 h (B), and retinas were processed for immunohistochemistry. A: Proliferating cell nuclear antigen (PCNA) immunohistochemistry (blue) reveals co-staining with GFP⁺ MG in the central-dorsal retina. Few MG do not express PCNA (arrowheads in A). PCNA also labels rod precursors in the ONL (double arrowheads). B: Most GFP⁺ MG continue to express PCNA. Arrows indicate MG associated with small PCNA⁺ progenitor clusters. Few PCNA⁺ cells are migrating to the ONL. ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer. Scale bars are 50 µm.

Expression Data

Gene:	GFP
Fish:	mi2001Tg
Condition:	high light intensity
Anatomical Term:	Muller cell
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.