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General Information
ZIRC
ZFIN ID: ZDB-FIG-150911-14
He et al., 2015 - Inflammatory signaling regulates hematopoietic stem and progenitor cell emergence in vertebrates. Blood   125(7):1098-106 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-5 to Long-pec
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-25 to Long-pec

Fig. S3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP la2Tg standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
la2Tg + CRISPR1-myd88 + CRISPR2-myd88 + CRISPR3-myd88 + CRISPR4-myd88 + CRISPR5-myd88 standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
la2Tg + CRISPR1-nfkb2 + CRISPR2-nfkb2 + CRISPR3-nfkb2 + CRISPR4-nfkb2 + CRISPR5-nfkb2 standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
la2Tg + CRISPR1-rela + CRISPR2-rela + CRISPR3-rela + CRISPR4-rela + CRISPR5-rela standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
la2Tg + CRISPR1-tlr4bb + CRISPR2-tlr4bb + CRISPR3-tlr4bb + CRISPR4-tlr4bb + CRISPR5-tlr4bb standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell IFL
s896Tg; zf169Tg standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + CRISPR1-myd88 + CRISPR2-myd88 + CRISPR3-myd88 + CRISPR4-myd88 + CRISPR5-myd88 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + CRISPR1-nfkb2 + CRISPR2-nfkb2 + CRISPR3-nfkb2 + CRISPR4-nfkb2 + CRISPR5-nfkb2 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + CRISPR1-rela + CRISPR2-rela + CRISPR3-rela + CRISPR4-rela + CRISPR5-rela standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + CRISPR1-tlr4bb + CRISPR2-tlr4bb + CRISPR3-tlr4bb + CRISPR4-tlr4bb + CRISPR5-tlr4bb standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
mCherry s896Tg; zf169Tg standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + CRISPR1-myd88 + CRISPR2-myd88 + CRISPR3-myd88 + CRISPR4-myd88 + CRISPR5-myd88 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + CRISPR1-nfkb2 + CRISPR2-nfkb2 + CRISPR3-nfkb2 + CRISPR4-nfkb2 + CRISPR5-nfkb2 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + CRISPR1-rela + CRISPR2-rela + CRISPR3-rela + CRISPR4-rela + CRISPR5-rela standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
s896Tg; zf169Tg + CRISPR1-tlr4bb + CRISPR2-tlr4bb + CRISPR3-tlr4bb + CRISPR4-tlr4bb + CRISPR5-tlr4bb standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell IFL
runx1 TU standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + CRISPR1-myd88 + CRISPR2-myd88 + CRISPR3-myd88 + CRISPR4-myd88 + CRISPR5-myd88 standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + CRISPR1-nfkb2 + CRISPR2-nfkb2 + CRISPR3-nfkb2 + CRISPR4-nfkb2 + CRISPR5-nfkb2 standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + CRISPR1-rela + CRISPR2-rela + CRISPR3-rela + CRISPR4-rela + CRISPR5-rela standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + CRISPR1-tlr4bb + CRISPR2-tlr4bb + CRISPR3-tlr4bb + CRISPR4-tlr4bb + CRISPR5-tlr4bb standard conditions Prim-5 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
la2Tg + CRISPR1-myd88 + CRISPR2-myd88 + CRISPR3-myd88 + CRISPR4-myd88 + CRISPR5-myd88 standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell decreased amount, abnormal
la2Tg + CRISPR1-nfkb2 + CRISPR2-nfkb2 + CRISPR3-nfkb2 + CRISPR4-nfkb2 + CRISPR5-nfkb2 standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell decreased amount, abnormal
la2Tg + CRISPR1-rela + CRISPR2-rela + CRISPR3-rela + CRISPR4-rela + CRISPR5-rela standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell decreased amount, abnormal
la2Tg + CRISPR1-tlr4bb + CRISPR2-tlr4bb + CRISPR3-tlr4bb + CRISPR4-tlr4bb + CRISPR5-tlr4bb standard conditions Long-pec intermediate cell mass of mesoderm hematopoietic cell decreased amount, abnormal
s896Tg; zf169Tg + CRISPR1-myd88 + CRISPR2-myd88 + CRISPR3-myd88 + CRISPR4-myd88 + CRISPR5-myd88 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
s896Tg; zf169Tg + CRISPR1-nfkb2 + CRISPR2-nfkb2 + CRISPR3-nfkb2 + CRISPR4-nfkb2 + CRISPR5-nfkb2 standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
s896Tg; zf169Tg + CRISPR1-rela + CRISPR2-rela + CRISPR3-rela + CRISPR4-rela + CRISPR5-rela standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
s896Tg; zf169Tg + CRISPR1-tlr4bb + CRISPR2-tlr4bb + CRISPR3-tlr4bb + CRISPR4-tlr4bb + CRISPR5-tlr4bb standard conditions Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell decreased amount, abnormal
Full text @ Blood