FIGURE

Fig. 2

ID

ZDB-FIG-150519-16

Publication

Xu et al., 2015 - Characterization of Tetratricopeptide Repeat-Containing Proteins Critical for Cilia Formation and Function

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Fig. 2

Screen for cilia-related TTC genes in zebrafish.

(A) The morphologies of zebrafish morphants at 72 hpf. Note that the morphants of ttc4, -9c, -25, -36, and -39c displayed severe body curving. (B) Quantification results for the curved body phenotype. Three independent experiments were performed. (C) and (D) Rescue experiments for the ttc morphants. The indicated MO was coinjected with either the corresponding MO-resistant mRNA or GFP mRNA into zebrafish embryos. The body curvature phenotype was assayed at 72 hpf. The numbers of embryos counted are listed over the histograms. Statistical results are from three independent experiments. Student’s t-test, ***P < 0.001. Error bars represent s.d.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-odad4 WT + MO1-ttc4 WT + MO1-ttc9c WT + MO1-ttc36 WT + MO1-ttc39c
Knockdown Reagents:	MO1-odad4 MO1-ttc4 MO1-ttc9c MO1-ttc36 MO1-ttc39c
Observed In:	trunk
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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