FIGURE

Fig. 2

ID

ZDB-FIG-140806-6

Publication

Teng et al., 2013 - Evaluating human cancer cell metastasis in zebrafish

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Fig. 2

Metastasis of primary human lung tumor cells in zebrafish. Cells derived from short term culture of a primary human lung tumor with an undifferentiated phenotype (#8) show extensive spread throughout the body of the fish (a, left) and invasion in vitro (a, right). In contrast, cells from a well-differentiated adenocarcinoma of the lung (#9) show only minimal dissemination in the fish and limited invasion in vitro. From cohort studies (b), the number of fish showing metastasis is significantly greater in #8 (shown as z-stack images using 40 × magnification). This relationship is maintained in in vitro invasion assays (b, right).

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Antibody Labeling

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Cancer